Ipratropium bromide in children with asthma.
نویسندگان
چکیده
Eighteen children between 6 and 14 years of age with perennial asthma were studied over two four-week treatment periods. Ipratropium bromide, given in addition to their current treatment, was compared with placebo using a double-blind crossover technique. The period of treatment with ipratropium was associated with a significant reduction in symptoms during both day and night and significantly higher morning peak expiratory flow rates.
منابع مشابه
Effect of nebulized ipratropium bromide on intraocular pressures in children.
STUDY OBJECTIVE To evaluate the effects of nebulized ipratropium bromide on intraocular pressures and pupillary responses in children with asthma. DESIGN A double-blind, randomized, crossover study. SETTING Children's Hospital of Winnipeg, University of Manitoba. PATIENTS OR PARTICIPANTS Age 6 to 17 years with asthma. INTERVENTION Nebulized ipratropium bromide added to albuterol sulfate...
متن کاملRandomized, double-blind, placebo-controlled trial of intravenous salbutamol and nebulized ipratropium bromide in early management of severe acute asthma in children presenting to an emergency department.
BACKGROUND In acute severe asthma, treatment must be initiated early to reverse the pathophysiology that may render airways less responsive to bronchodilation. The addition of nebulized ipratropium bromide to initial emergency department therapy improves pulmonary function, but it is unclear whether this approach results in earlier hospital discharge. The early use of bolus intravenous salbutam...
متن کاملRandomized trial of the addition of ipratropium bromide to albuterol and corticosteroid therapy in children hospitalized because of an acute asthma exacerbation.
OBJECTIVE To determine whether the addition of inhaled ipratropium bromide to inhaled albuterol and systemic corticosteroid therapy was more efficacious than inhaled albuterol and systemic corticosteroids alone in the inpatient treatment of acute asthma exacerbations in children. DESIGN Double-blind, randomized, placebo-controlled trial. SETTING Pediatric inpatient unit of a tertiary urban ...
متن کاملIpratropium bromide plus nebulized albuterol for the treatment of hospitalized children with acute asthma.
OBJECTIVE To determine whether the addition of repeated doses of nebulized ipratropium bromide (IB) to a standardized inpatient asthma care algorithm (ACA) for children with status asthmaticus improves clinical outcome. STUDY DESIGN Children with acute asthma (N = 210) age 1 to 18 years admitted to the ACA were assigned to the intervention or placebo group in randomized double-blind fashion. ...
متن کاملNebulized salbutamol vs salbutamol and ipratropium combination in asthma.
OBJECTIVE To see the additional benefit of combined frequent nebulization with salbutamol and ipratropium bromide in acute attack of asthma with moderate severity. METHODS Fifty asthmatic children in the age range of 6-14 years were divided into two equal groups. Group I children were nebulized with three doses of Salbutamol alone (0.03 ml/kg/dose) and Group II children were given combined ne...
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ورودعنوان ژورنال:
- Thorax
دوره 37 1 شماره
صفحات -
تاریخ انتشار 1982